Limone sul Garda is not just an enchanting place between the lake and the mountains, but also the cradle of a fascinating genetic mystery. Some Limone locals possess an exceptional and extremely rare genetic variant, the lipoprotein Apo A-1 Milano, which makes them naturally protected from the detrimental effects of “bad” cholesterol and high triglycerides.
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Limone, the magic lipoprotein
Many inhabitants of Limone del Garda carry the lipoprotein Apo A-1 Milano, which makes them resistant to the harmful effects of “bad cholesterol” and high triglycerides in blood, increasing the chances of extreme longevity.
Discovered in the 1970s by a team of researchers, this “magic lipoprotein” has immediately attracted the interest of the international scientific community. Its effects are surprising: carriers show a surprising resistance to cardiovascular disease and often experience exceptional longevity, with many inhabitants living past ninety in excellent health.
According to researchers, the mutation of this protein could be linked to the isolation in which Limone people lived until the 1960s, when their diet was simple and included locally-grown ingredients: olive oil, lemons, fish and a few other products from the land and the lake. An ancient, healthy and genuine diet, reason why the inhabitants of this small village are often referred to as the custodians of the secret of the Elixir of Life.
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